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Selleck Chemical LLCSupplier Diversity Partner Sunitinib Malate 50mg 341031-54-7  DFS Item

Manufacturer:  Selleck Chemical LLCSupplier Diversity Partner S104250MG

Sunitinib Malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1α. Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis.

Catalog No. 50-649-1


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