SUPT16H Mouse anti-Human, Clone: OTI8A1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527214
DescriptionTranscription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT , interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|SUPT16H; FACT; suppressor of Ty 16 homolog (S. cerevisiae); HGNC:11465; CDC68; FACTP140; FLJ10857; FLJ14010; SPT16/CDC68; chromatin-specific transcription elongation factor large subunit; FLJ34357; facilitates chromatin remodeling 140 kDa subunit|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 187-282 of SUPT16H produced in E.coli|
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