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Surfactant Protein B (Precursor) Ab-1 Mouse Monoclonal Antibody, Epredia™

Epredia™ Surfactant Protein B (Precursor) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

Supplier:  Epredia MS704PABX

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Catalog No. MS704PABX


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Description

Description

Pulmonary surfactant is a complex mixture of phospholipids and proteins that is secreted from type II cells in alveoli and reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventillation. Four distinct proteins isolated from pulmonary surfactant are termed surfactant proteins A, B, C, and D. SP-A (28-36kDa) and SP-D (43kDa) are collagenous carbohydrate-binding proteins, whereas SP-B (8-9kDa) and SP-C (4kDa) are non-collagenous hydrophobic proteins. SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns. Squamous cell and large cell carcinomas of the lung and nonpulmonary adenocarcinomas do not express SP-B. ProSP-B is glycosylated in the Golgi apparatus and undergoes carboxy- and amino-terminal proteolysis by a cathepsin D-like protease.

Host Species: Mouse

Clone: SPB01; same as 1-2-A5-9

Isotype: IgG2a/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant prosurfactant protein B

Molecular Weight: 42-46kDa

Positive Control: Lung adenocarcinoma

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Surfactant Protein B (Precursor) Ab-1
Monoclonal
1mg/mL
Mouse
200 μL
Cancer and Tumor Biology
Human, Rat
IgG2a κ
Immunofluorescence, Immunohistochemistry (Paraffin)
SPB01; same as 1-2-A5-9
Unconjugated
Recombinant pro-surfactant protein B
RUO
Primary
Concentrated
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