SUV39H1 Monoclonal Antibody (MG44), Active Motif™

Mouse Monoclonal Antibody

Supplier:  Active Motif 39785

Catalog No. 50-199-2850

Description

This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: SUV39H1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
• Gene Accession No.: O43463, O54864
• Gene Symbols: SUV39H1
• Immunogen: This SUV39H1 antibody was raised against a recombinant protein corresponding to amino acids 1-126 of mouse SUV39H1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: ChIP Assay, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
• Clone: MG44
• Conjugate: Unconjugated
• Gene: SUV39H1
• Gene Alias: AI852103; AL022883; DXHXS7466e; H3-K9-HMTase 1; Histone H3-K9 methyltransferase 1; Histone-lysine N-methyltransferase SUV39H1; histone-lysine N-methyltransferase, H3 lysine-9 specific 1; KMT1A; Lysine N-methyltransferase 1A; MG44; mIS6; Position-effect variegation 3-9 homolog; RGD1565028; Su(var)3-9 homolog 1; Suppressor of variegation 3-9 homolog 1; suppressor of variegation 3-9 homolog 1 (Drosophila); SUV39H; Suv39h histone methyltransferase; SUV39H1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 20937, 6839
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid