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Suz12 Polyclonal Antibody, Active Motif™
SDP

Rabbit Polyclonal Antibody

Supplier:  Active Motif 39358

Encompass

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Catalog No. 50-199-2691


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Description

Description

SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.
Specifications

Specifications

Suz12
Polyclonal
Unconjugated
SUZ12
2610028O16Rik; AI195385; AU016842; AW536442; ChET 9 protein; CHET9; Chromatin precipitated E2F target 9 protein; D11Ertd530e; JJAZ1; Joined to JAZF1 protein; KIAA0160; mKIAA0160; Polycomb protein Suz12; suppressor of zeste 12 homolog (Drosophila); Suppressor of zeste 12 protein homolog; SUZ12; SUZ12 polycomb repressive complex 2 subunit
Rabbit
Antigen affinity chromatography
RUO
23512, 52615
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot
Lot-Specific
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Q15022, Q80U70
SUZ12
This Suz12 antibody was raised against a peptide corresponding to the C-terminus of human Suz12.
10 μL
Primary
Human, Mouse
Antibody
IgG
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