SUZ12 Recombinant Rabbit Monoclonal Antibody (7H26L21), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Supplier: Thermo Scientific 702490
This antibody is predicted to react with Monkey, Bovine, Pig, Mouse Recombit rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombit rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.
|PBS with 0.09% sodium azide; pH 7.4|
|Protein corresponding to human SUZ12 [aa545-aa725]|
|Cynomolgus Monkey, Human|
|ChIP assay, Immunocytochemistry, Immunofluorescence, Western Blot|
|CHET9, JJAZ1, KIAA0160|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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