DescriptionPotent p38α inhibitor (IC50 = 9nM). Also inhibits p38β and JNK-2 (IC50 values are 90nM and 100nM respectively). Displays no significant activity at p38γ, p38δ, ERK-2 and JNK-1.
- Chemical Name: 6-Chloro-5-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]carbonyl-N,N,1-trimethyl-α-oxo-1H-indole-3-acetamide
- Formula: C26H27ClFN3O3
- CAS Number: 309913-42-6
- Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
- Purity: >98
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