Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

SYM 2206, Tocris Bioscience™

Click to view available options
Quantity:
10mg
50mg
173952-44-8
C20H22N4O3
366.421
OFUDZKKOKPGXOH-UHFFFAOYSA-N
+/--4-4-aminophenyl-1,2-dihydro-1-methyl-2-propylcarbamoyl-6,7-methylenedioxyphthalazine,1,3-dioxolo 4,5-g phthalazine-6 5h-carboxamide, 8-4-aminophenyl-5-methyl-n-propyl,biomol-nt_000221,8-4-aminophenyl-5-methyl-n-propyl-1,3-dioxolo 4,5-g phthalazine-6 5h-carboxamide,8-4-aminophenyl-5-methyl-n-propyl-5h-1,3 dioxolo 4,5-g phthalazine-6-carboxamide
5039877
8-(4-aminophenyl)-5-methyl-N-propyl-5H-[1,3]dioxolo[4,5-g]phthalazine-6-carboxamide
CCCNC(=O)N1C(C2=CC3=C(C=C2C(=N1)C4=CC=C(C=C4)N)OCO3)C
173952-44-8
C20H22N4O3
366.421
OFUDZKKOKPGXOH-UHFFFAOYSA-N
+/--4-4-aminophenyl-1,2-dihydro-1-methyl-2-propylcarbamoyl-6,7-methylenedioxyphthalazine,1,3-dioxolo 4,5-g phthalazine-6 5h-carboxamide, 8-4-aminophenyl-5-methyl-n-propyl,biomol-nt_000221,8-4-aminophenyl-5-methyl-n-propyl-1,3-dioxolo 4,5-g phthalazine-6 5h-carboxamide,8-4-aminophenyl-5-methyl-n-propyl-5h-1,3 dioxolo 4,5-g phthalazine-6-carboxamide
5039877
8-(4-aminophenyl)-5-methyl-N-propyl-5H-[1,3]dioxolo[4,5-g]phthalazine-6-carboxamide
CCCNC(=O)N1C(C2=CC3=C(C=C2C(=N1)C4=CC=C(C=C4)N)OCO3)C

Non-competitive AMPA antagonist

Novel, potent, non-competitive AMPA receptor antagonist (IC50 = 2.8 μM ). Acts allosterically at the same regulatory site as GYKI 52466 and 53655 and other benzodiazepines but does not bind to the central diazepine binding site. Selective for AMPA relative to kainate receptor sub-types. Similar potency to GYKI 53655. Anticonvulsant in vivo.
Quantity 50mg
Formula Weight 366.42
Percent Purity >99%
Chemical Name or Material SYM 2206

Recommended Storage : Store at Room Temperature