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SYM 2206, Tocris Bioscience™

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Quantity:
10mg
50mg

Chemical Identifiers

173952-44-8
C20H22N4O3
366.421
OFUDZKKOKPGXOH-UHFFFAOYSA-N
(±)-4-(4-Aminophenyl)-1, 2-dihydro-1-methyl-2-propylcarbamoyl-6, 7-methylenedioxyphthalazine
5039877
8-(4-aminophenyl)-5-methyl-N-propyl-5H-[1,3]dioxolo[4,5-g]phthalazine-6-carboxamide
CCCNC(=O)N1C(C2=CC3=C(C=C2C(=N1)C4=CC=C(C=C4)N)OCO3)C

Non-competitive AMPA antagonist

Novel, potent, non-competitive AMPA receptor antagonist (IC50 = 2.8 μM ). Acts allosterically at the same regulatory site as GYKI 52466 and 53655 and other benzodiazepines but does not bind to the central diazepine binding site. Selective for AMPA relative to kainate receptor sub-types. Similar potency to GYKI 53655. Anticonvulsant in vivo.
Quantity 50mg
Formula Weight 366.42
Chemical Name or Material SYM 2206
Grade >99%

Recommended Storage : Store at Room Temperature