Invitrogen™ Synaptotagmin 7 Monoclonal Antibody (N275/14)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527654

Catalog No. PIMA527654

Description

1 μg/mL of MA5-27654 was sufficient for detection of Synaptotagmin-7 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 45kDa. Does not cross-react with Synaptotagmin-6 (or others). Can identify other isoforms bands at approximately 65kD. This antibody was formerly sold as clone S275-14.

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: Synaptotagmin 7
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: O43581, Q62747, Q9R0N7
• Gene Symbols: SYT7
• Immunogen: Fusion protein amino acids 150-239 (Cytoplasmic C2A domain) of mouse Synaptotagmin-7.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
• Clone: N275/14
• Conjugate: Unconjugated
• Gene: SYT7
• Gene Alias: AI851541; B230112P13Rik; IPCA7; IPCA-7; PCANAP7; Prostate cancer-associated protein 7; Protein Syt7; synaptotagmin 7; synaptotagmin VII; Synaptotagmin-7; SYT7; SYT-7; SytVII; SYT-VII
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 54525, 59267, 9066
• Content And Storage: -20°C
• Form: Liquid