Invitrogen™ SYNE3 Polyclonal Antibody

Catalog No.	Quantity
PIPA5101702	100 μL

Catalog No. PIPA5101702

Supplier: Invitrogen™ PA5101702

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total C14orf49.

As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells. [UniProt].

Specifications

• Antigen: SYNE3
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: SYNE3
• Gene Accession No.: Q4FZC9, Q6ZMZ3
• Gene Alias: C14orf139; C14orf49; KASH domain-containing protein 3; KASH3; LINC00341; Nesp3; nesprin-3; NET53; Nuclear envelope spectrin repeat protein 3; RGD1304563; spectrin repeat containing nuclear envelope family member 3; spectrin repeat containing, nuclear envelope family member 3; SYNE3
• Gene Symbols: SYNE3
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human SYNE3(Accession Q6ZMZ3), corresponding to amino acid residues V168-V218.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 161176, 212073
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov