Thermo Scientific Lab Vision Synuclein Ab-2, Mouse Monoclonal Antibody
Provide accurate, reproducible results Thermo Scientific Synuclein Ab-2, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific MS1572P0
Provide accurate, reproducible results Thermo Scientific Synuclein Ab-2, Mouse Monoclonal Antibody.Synnuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's (PD) and breast cancer. In AD, a peptide derived from α-synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of α synuclein has been linked to many familial cases of PD. In breast cancer increased expression of γ synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.
Host Species: Mouse
Species Reactivity: Human. Does not react with mouse and rat. Others not known.
Epitope: Not determined
Immunogen: Human recombinant α-synuclein
Molecular Weight: ~14kDa
Positive Control: Brain
Cellular Localization: Neuronal cytosol and presynaptic terminals
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
USA: RUO; Int'l: RUO
|Purified Ab with BSA and Azide|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Human recombinant alpha-synuclein|
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