Synuclein Ab-2 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results Epredia™ Synuclein Ab-2, Mouse Monoclonal Antibody.

Supplier:  Epredia MS1572R1

Catalog No. MS1572R1

Description

Synnuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's (PD) and breast cancer. In AD, a peptide derived from α-synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of α synuclein has been linked to many familial cases of PD. In breast cancer increased expression of γ synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.

Host Species: Mouse

Clone: syn211

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: Not determined

Immunogen: Human recombinant α-synuclein

Molecular Weight: ∽14kDa

Positive Control: Brain

Cellular Localization: Neuronal cytosol and presynaptic terminals

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Synuclein Ab-2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 1 mL
• Research Discipline: Neuroscience
• Target Species: Human
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: syn211
• Formulation: Ready-to-use for IHC (UVLP)
• Immunogen: Human recombinant alpha-synuclein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Prediluted