SYT10 Mouse anti-Human, Mouse, Rat, Clone: S269-73, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527591
DescriptionSYT10 is a Ca2+ sensor specifically required for the Ca2+-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. SYT10 is not involved in Ca2+-dependent synaptic vesicle exocytosis. It acts through Ca2+ and phospholipid binding to the C2 domain: Ca2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.
|PBS with 50% glycerol and 0.09% sodium azide; pH 7.4|
|O08625, Q6XYQ8, Q9R0N4|
|SYT10, SYT-10, Synaptotagmin 10, Synaptotagmin X, SytX, P65, SVP65, DKFZp781D2042, SYT|
|341359, 54526, 60567|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Fusion protein amino acids 248-335 (Cytoplasmic C2A domain) of mouse Synaptotagmin-10|
|Human, Mouse, Rat|
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