Tocris™ T 5601640

Selective LIMK2 inhibitor; antitumor

Manufacturer: Tocris™ 5269/50

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Catalog No. 52-695-0

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For Research Use Only


    Inhibitors T 5601640
    Product Type T 5601640
    Purity >99
    Molecular Weight 389.33
    Quantity 50mg

    Selective LIM kinase 2 (LIMK2) inhibitor; inhibits cofilin phosphorylation in cells that overexpress LIMK2 but not LIMK1. Attenuates the growth of several cancer cell lines. Reduces phospho-cofilin levels and Panc-1 tumor size in a mouse xenograft model.

    • Chemical Name: 3-Methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide
    • Formula: C19H14F3N3O3
    • CAS Number: 924473-59-6
    • Solubility: Soluble to 50mM in DMSO
    • Purity: >99

  • Description & Specifications

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