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TACC3 Mouse anti-Human, Clone: OTI3B1, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA501254

Catalog No. 50-167-2396


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Description

Description

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
Specifications

Specifications

TACC3
Monoclonal
0.44 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9Y6A5
ERIC-1, ERIC1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
10460
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI3B1
Unconjugated
TACC3
Liquid
TACC3
Full length human recombit protein of human TACC3 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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