TACR3 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 223341AP
DescriptionSubstance P (SP) and neurokinin-A (NK-A) are members of the tachykinins, and they function as modulators of the immune and hematopoietic systems. The tachykinins interact with each of three cloned neurokinin (NK) receptors (NK-1R, NK-2R, NK-3R), with SP and NK-A exhibiting binding preferences for NK-1R and NK-2R, respectively. NK-4R shares close homology with NK-3R, and both have nearly identical pharmacologicl properties. In the normal ileum and colon, NK-1R and NK-2R are localized to smooth muscle cells of the muscularis mucosae and propria and to a few inflammatory cells of the lamina propria. NK-1R expression is also found in the muscular wall of submucosal blood vessels, enteric neurons and, to a lesser degree, in surface epithelial cells. NK-3R is found in the spinal cord in both lamina X and lamina II.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|Neurokinin B receptor, Neuromedin K receptor, NK 3 receptor, NK 3R, NK3R, NKR, TAC3R, TAC3RL, tachykinin receptor 3, TACR3|
|TACR3 Fusion Protein Ag17808|
|Antigen Affinity Chromatography|
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