TAG-72 Mouse anti-Human, Rat, Bovine, Canine, Alexa Fluor™ 750, Clone: CA72/733, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234591AF750
DescriptionTAG-72 Monoclonal specifically detects TAG-72 in Human, Rat, Bovine, Canine samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
|Alexa Fluor 750|
|50 mM sodium borate with 0.05% sodium azide|
|Protein A or G purified|
|Human, Rat, Bovine, Canine|
|Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)|
|Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen|
|CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72|
|Recombinant human TAG-72 protein|
|Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.|
|Store at 4°C in the dark.|
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