TAG-72 Mouse anti-Human, Rat, Bovine, Canine, Allophycocyanin/Cy7, Clone: CC49, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP233128APCCY7

Catalog No. N233128APC7

Description

TAG-72 Monoclonal antibody specifically detects TAG-72 in Human, Rat, Bovine, Canine samples. It is validated for Flow Cytometry.

Specifications

• Antigen: TAG-72
• Clone: CC49
• Dilution: Flow Cytometry
• Format: Conjugated, Purified
• Host Species: Mouse
• Isotype: IgG1 Kappa
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

• Applications: Flow Cytometry
• Conjugate: APC-Cyanine7
• Formulation: PBS with 0.05% Sodium Azide
• Gene Alias: CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72
• Immunogen: Purified TAG-72 protein
• Purification Method: Protein A purified
• Storage Requirements: Store at 4°C in the dark. Do not freeze.
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Bovine, Canine, Human, Rat