Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Tocris™ TAK 165

Potent and selective ErbB2 inhibitor

Manufacturer:  Tocris™ 3599/50

 View more versions of this product

Catalog No. 35-995-0R

  Check Availability
Add to cart


For Research Use Only



Potent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC50 = 6nM) that displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC50 = 5nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo.
  • Chemical Name: 1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole
  • Formula: C25H23F3N4O2
  • CAS Number: 366017-09-6
  • Solubility: Soluble to 75mM in DMSO and to 5mM in ethanol
  • Purity: >99
Description & Specifications


TAK 165
TAK 165
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit