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TALDO1 Mouse anti-Human, Clone: OTI1E5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527221

Catalog No. PIMA527221


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Description

Description

Proper cell growth, differentiation and survival relies on a series of enzymes involved in complex redox and metabolic pathways. One of these enzymes, Transaldolase, contributes to the generation of NADPH in the nonoxidative phase of the pentose phosphate pathway (PPP) and is important for maintaining metabolite balance. In conjunction with several other enzymes, Transaldolase works to maintain the mitochondrial transmembrane potential by producing both ribose-5-phosphate and NADPH for use in nucleic acid and lipid biosynthesis. The role of Transaldolase in the PPP of spermatoza is of significant importance, as deficiencies in Transaldolase are directly related with male infertility due to loss of sperm structure and function. Mutations in the gene encoding Transaldolase are thought to play a role in multiple sclerosis and are the direct cause of hepatosplenomegaly and telangiectases of the skin.
Specifications

Specifications

TALDO1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P37837
TAL, TAL-H, TALDOR, TALH, dihydroxyacetone transferase, glycerone transferase, transaldolase
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
6888
Immunohistochemistry (Paraffin), Western Blot
OTI1E5
Unconjugated
TALDO1
Liquid
TALDO1
Full length human recombit protein of TALDO1 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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