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Talin 1 Mouse anti-Human, Clone: GT24212, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527787

Catalog No. PIMA527787


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Description

Description

Positive Control: H1299 Predicted Reactivity: Mouse (99%), Rat (99%), Zebrafish (92%), Chicken (93%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Talin encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
Specifications

Specifications

Talin 1
Monoclonal
1 mg/ml
PBS with no preservative
Q9Y490
ILWEQ, TLN, TLN1, Talin-1, talin 1
Mouse
IgG1
100 μl
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
7094
Western Blot
GT24212
Unconjugated
TLN1
Liquid
TLN1
Recombit protein encompassing a sequence within the C-terminus region of human Talin-1. The exact sequence is proprietary.
Protein G
RUO
Antibody
Monoclonal
Human
Documents
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