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  7. Talniflumate, Tocris Bioscience™

Talniflumate, Tocris Bioscience™

Catalog Number 251050
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
66898-62-2
C21H13F3N2O4
414.34
MFCD00866135
ANMLJLFWUCQGKZ-UHFFFAOYNA-N
talniflumate, somalgen, lomucin, talniflumato, talniflumate usan:inn, talniflumatum inn-latin, talniflumato inn-spanish, phthalidyl 2-3-trifluoromethylanilino nicotinate, 3-phthalidyl ester of 2-3-trifluoromethyl phenyl amino-3-pyridinecarboxylic acid, phthalidyl 2-alpha,alpha,alpha-trifluoro-m-toluidino nicotinate
48229
3-oxo-1,3-dihydro-2-benzofuran-1-yl 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylate
FC(F)(F)C1=CC=CC(NC2=NC=CC=C2C(=O)OC2OC(=O)C3=CC=CC=C23)=C1
This item is not returnable. View return policy
66898-62-2
C21H13F3N2O4
414.34
MFCD00866135
ANMLJLFWUCQGKZ-UHFFFAOYNA-N
talniflumate, somalgen, lomucin, talniflumato, talniflumate usan:inn, talniflumatum inn-latin, talniflumato inn-spanish, phthalidyl 2-3-trifluoromethylanilino nicotinate, 3-phthalidyl ester of 2-3-trifluoromethyl phenyl amino-3-pyridinecarboxylic acid, phthalidyl 2-alpha,alpha,alpha-trifluoro-m-toluidino nicotinate
48229
3-oxo-1,3-dihydro-2-benzofuran-1-yl 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylate
FC(F)(F)C1=CC=CC(NC2=NC=CC=C2C(=O)OC2OC(=O)C3=CC=CC=C23)=C1

Description

CaCC blocker and Cl-/HCO3- exchange inhibitor

Calcium-activated chloride channel (CaCC) (hCLCA1/mCLCA3) blocker; reduces mucin synthesis and release in cell culture and animal models. Possesses anti-inflammatory actions via inhibition of cyclooxygenases and inhibits Cl-/HCO3- exchanger activity. Increases survival in a cystic fibrosis mouse model of distal intestinal obstructive syndrome.
Quantity 50 mg
Formula Weight 414.34
Percent Purity >99%
Chemical Name or Material Talniflumate

Safety and Handling

Recommended Storage Store at +4°C
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