TAOK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 211881AP
The immunogen of this antibody is 742-969 aa of human TAOK2 protein isoform Alpha. This antibody mainly detects the isoforms 1, 3, and 4. It does not detect isoform 2.In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEK ) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonist to the stress -responsive p38 MAPK (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|Q6ZQ29, Q9JLS3, Q9UL54|
|hKFC C, KIAA0881, Kinase from chicken homolog C, MAP3K17, PSK, PSK 1, PSK1, TAO kinase 2, TAO1, TAO2, TAOK2|
|381921, 64666, 9344|
|Immunoprecipitation, Western Blot|
|TAOK2 Fusion Protein Ag15521|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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