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TAOK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 211881AP

Catalog No. 50-173-3309


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Description

Description

The immunogen of this antibody is 742-969 aa of human TAOK2 protein isoform Alpha. This antibody mainly detects the isoforms 1, 3, and 4. It does not detect isoform 2.

In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEK ) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonist to the stress -responsive p38 MAPK (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.
Specifications

Specifications

TAOK2
0.26 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q6ZQ29, Q9JLS3, Q9UL54
hKFC C, KIAA0881, Kinase from chicken homolog C, MAP3K17, PSK, PSK 1, PSK1, TAO kinase 2, TAO1, TAO2, TAOK2
Rabbit
IgG
150 μL
-20°C
Primary
381921, 64666, 9344
Immunoprecipitation, Western Blot
Unconjugated
TAOK2
Liquid
Taok2
TAOK2 Fusion Protein Ag15521
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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