TAS2R8 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5102258

Catalog No. PIPA5102258

Description

Antibody detects endogenous levels of total TAS2R8.

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.

Specifications

• Antigen: TAS2R8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAS2R8
• Gene Alias: T2R8; TAS2R8; taste 2 receptor member 8; taste receptor family B member 5; Taste receptor type 2 member 8; taste receptor, family B, member 5; taste receptor, type 2, member 8; TRB5
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50836
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9NYW2
• Gene Symbols: TAS2R8
• Immunogen: A synthesized peptide derived from human TAS2R8(Accession Q9NYW2), corresponding to amino acid residues V52-C102.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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