Invitrogen™ TAUT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537460

Catalog No. PIPA537460

Description

This antibody detects endogenous protein at a molecular weight of 70 kDa. Purity is >95% by SDS-PAGE.

Taurine is an abundant organic osmolyte that possesses antioxidant and immunomodulatory properties and plays a role in cell volume homeostasis. Taurine is taken up into cells via the taurine transporter (TAUT). TAUT, which is sodium- and chloride-dependent, is a multi-pass membrane protein belonging to the sodium neurotransmitter symporter (SNF) family of proteins. TNF alpha upregulates TAUT expression, while phosphorylation on Serine 322 downregulates it. Overexpression of TAUT protects renal cells from cisplatin-induced nephrotoxicity.

Specifications

• Antigen: TAUT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC6A6
• Gene Alias: AA589629; C80501; MGC10619; MGC131729; OTTHUMP00000208177; OTTHUMP00000208180; SC6A6; Slc6a6; Sodium- and chloride-dependent taurine transporter; Solute carrier 6 ,member 6 (taurine transporter); solute carrier family 6 (neurotransmitter transporter), member 6; solute carrier family 6 (neurotransmitter transporter, taurine), member 6; solute carrier family 6 member 6; solute carrier family 6, member 6; Taurine Transporter; taurine/beta-alanine transporter; TAUT
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21366, 29464, 6533
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide; pH 7.2
• Gene Accession No.: O35316, P31641, P31643
• Gene Symbols: SLC6A6
• Immunogen: Synthetic peptide corresponding to amino acids 570-620 of human TAUT.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG