TBC1D17 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 204821AP
DescriptionProbable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|TBC1 domain family member 17, TBC1 domain family, member 17, TBC1D17|
|233204, 292886, 79735|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|TBC1D17 Fusion Protein Ag14358|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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