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TBC1D22A Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550801

Catalog No. PA550801


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Description

Description

The antibody detects endogenous levels of total TBC1D22A protein.

TBC1D22A (TBC1 domain family, member 22A), also known as C22orf4, is a 517 amino acid protein that contains one Rab-GAP TBC domain and is thought to function as a GTPase-activating protein for Rab family members. Multiple isoforms of TBC1D22A exist due to alternative splicing events. The gene encoding TBC1D22A maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
Specifications

Specifications

TBC1D22A
Polyclonal
Unconjugated
TBC1D22A
Liquid
TBC1D22A
Fusion protein of human TBC1 domain family, member 22A
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1.4 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q8WUA7
C22orf4
Rabbit
IgG
100 μL
-20°C
Primary
25771
Documents
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