TBX1 Mouse anti-Human, Clone: OTI1C2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526348
DescriptionTBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|CAFS, CTHM, DGCR, DGS, DORV, TBX1C, TGA, VCFS, T-box 1 transcription factor C, T-box transcription factor TBX1, Testis-specific T-box protein, brachyury|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of TBX1 produced in HEK293T cell|
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