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Tocris Bioscience™ TC-E 5001

Potent tankyrase inhibitor

Manufacturer:  Tocris Bioscience™ 5049/10

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Catalog No. 504910R


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Description

Description

Dual tankyrase (TNKS) inhibitor (Kd values are 79 and 28 nM for TNKS1 and TNKS2 respectively, IC50 = 33 nM for TNKS2) that is devoid of activity at PARP1 and PARP2 (IC50 >19 μM). Inhibits Wnt signaling and stabilizes Axin2 levels.
Specifications

Specifications

TC-E 5001
>98
10mg
TC-E 5001
409.46
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