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Tocris™ TC-E 5001

Potent tankyrase inhibitor

Manufacturer:  Tocris™ 5049/10

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Catalog No. 504910R


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Disclaimers:

For Research Use Only


Specifications

Description

Dual tankyrase (TNKS) inhibitor (Kd values are 79 and 28nM for TNKS1 and TNKS2 respectively, IC50 = 33nM for TNKS2) that is devoid of activity at PARP1 and PARP2 (IC50 >19µM). Inhibits Wnt signaling and stabilizes Axin2 levels.
  • Chemical Name: 3-(4-Methoxyphenyl)-5-[[[4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazole
  • Formula: C20H19N5O3S
  • CAS Number: 865565-29-3
  • Solubility: Soluble to 100mM in DMSO
  • Purity: >98
Description & Specifications

Specifications

TC-E 5001
>98
10mg
TC-E 5001
409.46
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