Tocris™ TC-E 5001

Potent tankyrase inhibitor

Manufacturer: Tocris™ 5049/10

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Catalog No. 504910R

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For Research Use Only


    Inhibitors TC-E 5001
    Purity >98
    Molecular Weight 409.46
    Quantity 10mg
    Product Type TC-E 5001

    Dual tankyrase (TNKS) inhibitor (Kd values are 79 and 28nM for TNKS1 and TNKS2 respectively, IC50 = 33nM for TNKS2) that is devoid of activity at PARP1 and PARP2 (IC50 >19µM). Inhibits Wnt signaling and stabilizes Axin2 levels.

    • Chemical Name: 3-(4-Methoxyphenyl)-5-[[[4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazole
    • Formula: C20H19N5O3S
    • CAS Number: 865565-29-3
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

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