Tocris™ TC-E 5006

gamma-secretase modulator; reduces Abeta42 levels

Manufacturer: Tocris™ 4898/10

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Catalog No. 48-981-0

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For Research Use Only


    Product Type TC-E 5006
    Inhibitors TC-E 5006
    Purity >98
    Molecular Weight 499.54
    Quantity 10mg

    γ-secretase modulator. Reduces Aβ42 levels in vitro (EC50 = 390nM) and in vivo. Orally bioavailable.

    • Chemical Name: 6-[(4-Fluorophenyl)(4-methyl-1-piperidinyl)methyl]-a-methyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-acetic acid
    • Formula: C29H29F4NO2
    • CAS Number: 1257395-14-4
    • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
    • Purity: >98

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