Tocris™ TC Mps1 12

Potent and selective Mps1 kinase inhibitor

Manufacturer: Tocris™ 4750/50

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Catalog No. 47-505-0

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    Specifications

    Product Type TC Mps1 12
    Inhibitors TC Mps1 12
    Purity >99
    Molecular Weight 324.38
    Quantity 50mg

    Potent and selective monopolar spindle 1 (Mps1) inhibitor (IC50 = 6.4nM). Selective for Mps1 over a panel of 95 kinases including JNK. Inhibits A549 lung carcinoma cell proliferation and attenuates A549 cell xenograft growth in mice. Orally active.

    • Chemical Name: 4-[[4-Amino-5-cyano-6-[(1,1-dimethylethyl)amino]-2-pyridinyl]amino]benzamide
    • Formula: C17H20N6O
    • CAS Number: 1206170-62-8
    • Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol with gentle warming
    • Purity: >99

  • Description & Specifications

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