Tocris™ TC-S 7004

Potent and selective DYRK1A/B inhibitor

Manufacturer: Tocris™ 5088/10

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Catalog No. 50-881-0RD

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For Research Use Only


    Specifications

    Description TC-S 7004
    Molecular Weight 498.32
    Purity >98
    Quantity 10mg
    Product Type TC-S 7004

    Potent and selective DYRK1A/B inhibitor (IC50 values are 22 and 68nM respectively). Selective for DYRK1A/B over a panel of other kinases. Reduces accumulation of quiescent Panc1 pancreatic cancer cells in G0 under serum free conditions. Also induces DNA damage and apoptosis in quiescent Panc1 cells.

    • Chemical Name: N-[2-Chloro-5-[[[(3-chlorophenyl)methyl]amino]carbonyl]phenyl]-7,8-dihydro-2-methoxy-7-oxopyrido[2,3-d]pyrimidine-6-carboxamide
    • Formula: C23H17Cl2N5O4
    • CAS Number: 1146757-96-1
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

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