Tocris™ TC-S 7004

Potent and selective DYRK1A/B inhibitor

Manufacturer: Tocris™ 5088/10

 View more versions of this product

Catalog No. 50-881-0RD

  Check Availability
Add to Cart


For Research Use Only


    Description TC-S 7004
    Molecular Weight 498.32
    Purity >98
    Quantity 10mg
    Product Type TC-S 7004

    Potent and selective DYRK1A/B inhibitor (IC50 values are 22 and 68nM respectively). Selective for DYRK1A/B over a panel of other kinases. Reduces accumulation of quiescent Panc1 pancreatic cancer cells in G0 under serum free conditions. Also induces DNA damage and apoptosis in quiescent Panc1 cells.

    • Chemical Name: N-[2-Chloro-5-[[[(3-chlorophenyl)methyl]amino]carbonyl]phenyl]-7,8-dihydro-2-methoxy-7-oxopyrido[2,3-d]pyrimidine-6-carboxamide
    • Formula: C23H17Cl2N5O4
    • CAS Number: 1146757-96-1
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

Related Products

Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit