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TCAP Mouse anti-Human, Clone: OTI11H10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526987

Catalog No. PIMA526987


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Description

Description

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Specifications

Specifications

TCAP
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
O15273
Titin-cap (telethonin), CMD1N, LGMD2G, T-cap, TELE, telethonin
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
8557
Immunohistochemistry (Paraffin), Western Blot
OTI11H10
Unconjugated
TCAP
Liquid
TCAP
Full length human recombit protein of TCAP produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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