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TCF7 Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer:  Active MotifSupplier Diversity Partner 61580

Encompass

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Catalog No. 50-199-3518


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Description

Description

TCF7 (transcriptional factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ and CD8+ immature thymocytes. Isoforms for TCF7 lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. TCF7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. It may also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3, and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
Specifications

Specifications

TCF7
Western Blot
Unconjugated
TCF7
Liquid
Rabbit
IgG
10 μL
-20°C, Avoid Freeze/Thaw Cycles
Primary
6932
TCF7
Lot-Specific
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
P36402
AI465550; HMG-box; OTTHUMP00000159390; OTTHUMP00000159391; T cell factor-1; T-cell factor 1; T-cell specific; T-cell-specific transcription factor 1; Tcf1; Tcf-1; Tcf7; TCF-7; Transcription factor 7; transcription factor 7 (T-cell specific, HMG-box); transcription factor 7, T cell specific; transcription factor 7, T-cell specific
This antibody was raised against a peptide within the N-terminal region of human TCF7.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
SDS
Documents
Product Certifications
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