TCP-1 beta Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA593047

Catalog No. PIPA593047

Description

Immunogen sequence: GGSLADSYLD EGFLLDKKIG VNQPKRIENA KILIANTGMD TDKIKIFGSR VRVDSTAKVA EIEHAEKEKM KEKVERILKH GINCFINRQL IYNYPEQLFG AAGVMAIEHA DFAGVERLAL VTGGEIASTF DHPELVKLGS CKLIEEVMIG EDKLIHFSGV ALGEACTIVL RGATQQILDE AERSLHDALC VLAQTVKDSR TVYGGGCSEM LMAHAVTQLA NRTPGKEAVA MESYAKALRM LPTIIADNAG YDSADLVAQL RAAHSEGNTT AGLDMREGTI GDMAILGITE SFQVKRQVLL SAAEAAEVIL RVDNIIKAAP RKRVPDHHPC; Positive Samples: MCF7, SKOV3, A-549, HT-29, Mouse spleen, Mouse ovary, Mouse heart; Cellular Location: Cytoplasm

TCP-1 beta is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). The CCT complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the TCP-1 beta gene have been observed but not thoroughly characterized. A disease associated with TCP-1 beta protein dysfunction include epididymo-orchitis.

Specifications

• Antigen: TCP-1 beta
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCT2
• Gene Symbols: CCT2
• Immunogen: Recombit fusion protein containing a sequence corresponding to amino acids 206-535 of human CCT2
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunofluorescence, Immunoprecipitation, Western Blot
• Concentration: 5.63 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P78371, P80314
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10576, 12461
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid