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TCP-1 zeta Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551069

Catalog No. PA551069


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Description

Description

TCP-1 zeta / CCT6A Polyclonal Antibody detects endogenous levels of TCP-1 zeta / CCT6A protein.

The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 alpha, beta, gamma, delta, epsilon, zeta, eta and theta, each encoded by a different gene. Two zeta subunits have been described: TCP-1 zeta (also designated TCP-1 zeta1) and TCP-1 zeta2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.
Specifications

Specifications

TCP-1 zeta
Polyclonal
Unconjugated
CCT6A
Liquid
CCT6A
Synthesized peptide derived from the Internal region of human TCP-1 &No.950;.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
ELISA, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
P40227, P80317
CCT6A, CCT6, CCTZ, T-complex protein 1 subunit zeta, TCP-1-zeta, Acute morphine dependence-related protein 2, CCT-zeta-1, HTR3, Tcp20
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
12466, 288620, 908
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