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TCP-1 epsilon Mouse anti-Human, Clone: GT639, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527824

Catalog No. PIMA527824


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Description

Description

Positive Control: 293T, A431, HeLa, HepG2 Predicted Reactivity: Mouse (94%), Rat (94%), Zebrafish (83%), Xenopus laevis (86%), Pig (96%), Chicken (88%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (95%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by TCP1 epsilon is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in TCP1 epsilon cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13.
Specifications

Specifications

TCP-1 epsilon
Monoclonal
1 mg/ml
PBS with no preservative
P48643
chaperonin containing TCP1, subunit 5 (epsilon), TCP-1-epsilon, CCT-epsilon, CCT5, CCTE
Mouse
IgG1
100 μl
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
22948
Immunoprecipitation, Western Blot
GT639
Unconjugated
CCT5
Liquid
CCT5
Recombit protein encompassing a sequence within the center region of human TCP1 epsilon. The exact sequence is proprietary.
Protein G
RUO
Antibody
Monoclonal
Human
Documents
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