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TCR β Chain Hamster anti-Mouse, Brilliant Violet 786, Clone: H57-597, BD Optibuild™

Armenian Hamster Monoclonal Antibody

Supplier:  BD Biosciences 742484/DUP

Catalog No. BDB742484

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.


Description

Description

The H57-597 antibody reacts with a common epitope of theβchain of the T-cell Receptor (TCR) complex onαβTCR-expressing thymocytes, peripheral T lymphocytes, NK1.1+ thymocytes, and NK-T cells of all mouse strains tested. It does not react withγδTCR-bearing T cells. In the fetal and adult thymus, the TCRβ-chain may form homodimers or pair with the pre-TCRα-chain on the surface of immature thymocytes before TCRα-chain expression. Plate-bound or soluble H57-597 antibody activatesαβTCR-bearing T cells, and plate-bound mAb can induce apoptotic death.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter). BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm. BV786 offers a bright choice for the 6th detector off the violet laser.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TCR β Chain
H57-597
Brilliant Violet 786
Tcrb, TCRbeta, TCRβ, T cell receptor beta chain
TCR affinity-purified from mouse T-cell hybridoma DO-11.10
50 μg
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
0.2mg/mL
Aqueous buffered solution containing ≤0.09% sodium azide.
Armenian Hamster
Affinity Purified
RUO
Mouse
IgG2 λ1
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