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TCS 46b, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
302799-86-6
C22H23N3O
345.446
JJEXWPHPFZLTCU-UHFFFAOYSA-N
tcs 46b,1,3-dihydro-5-3-4-phenylmethyl-1-2h-benzimidazol-2-one,5-3-4-benzylpiperidino-1-propynyl-1h-benzimidazole-2 3h-one,5-3-4-benzylpiperidin-1-yl prop-1-ynyl-1h-benzo d imidazol-2 3h-one,5-3-4-benzyl-piperidin-1-yl-prop-1-ynyl-1,3-dihydro-benzoimidazol-2-one
9863010
5-[3-(4-benzylpiperidin-1-yl)prop-1-ynyl]-1,3-dihydrobenzimidazol-2-one
C1CN(CCC1CC2=CC=CC=C2)CC#CC3=CC4=C(C=C3)NC(=O)N4
This item is not returnable. View return policy
302799-86-6
C22H23N3O
345.446
JJEXWPHPFZLTCU-UHFFFAOYSA-N
tcs 46b,1,3-dihydro-5-3-4-phenylmethyl-1-2h-benzimidazol-2-one,5-3-4-benzylpiperidino-1-propynyl-1h-benzimidazole-2 3h-one,5-3-4-benzylpiperidin-1-yl prop-1-ynyl-1h-benzo d imidazol-2 3h-one,5-3-4-benzyl-piperidin-1-yl-prop-1-ynyl-1,3-dihydro-benzoimidazol-2-one
9863010
5-[3-(4-benzylpiperidin-1-yl)prop-1-ynyl]-1,3-dihydrobenzimidazol-2-one
C1CN(CCC1CC2=CC=CC=C2)CC#CC3=CC4=C(C=C3)NC(=O)N4

Orally active, subtype-selective NR1A/NR2B antagonist

Orally active, subtype-selective GluN1A/GluN2B (formally NR1A/NR2B) NMDA receptor antagonist (IC 50 values are 5.3, 35000 and > 100000 nM for GluN1A/2B (NR1A/2B), GluN1A/2B (NR1A/2B) and GluN1A/2C (NR1A/2C) receptor subtypes respectively). Potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration. Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.
Quantity 50mg
Formula Weight 345.44
Percent Purity >98%
Chemical Name or Material TCS 46b

Recommended Storage : Store at Room Temperature