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TCS JNK 6o, Tocris Bioscience™

Catalog Number p-4784665
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
894804-07-0
C18H20N4O4
356.382
KQMPRSZTUSSXND-UHFFFAOYSA-N
jnk inhibitor viii, aminopyridine deriv. 2, tcs jnk 6o, n-4-amino-5-cyano-6-ethoxypyridin-2-yl-2-2,5-dimethoxyphenyl acetamide, kinome_3020, d00hva, aminopyridine-based inhibitor 6o, n-4-amino-5-cyano-6-ethoxy-2-pyridinyl-2,5-dimethoxybenzeneacetamide
11624601
N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide
CCOC1=C(C(=CC(=N1)NC(=O)CC2=C(C=CC(=C2)OC)OC)N)C#N
This item is not returnable. View return policy
894804-07-0
C18H20N4O4
356.382
KQMPRSZTUSSXND-UHFFFAOYSA-N
jnk inhibitor viii, aminopyridine deriv. 2, tcs jnk 6o, n-4-amino-5-cyano-6-ethoxypyridin-2-yl-2-2,5-dimethoxyphenyl acetamide, kinome_3020, d00hva, aminopyridine-based inhibitor 6o, n-4-amino-5-cyano-6-ethoxy-2-pyridinyl-2,5-dimethoxybenzeneacetamide
11624601
N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide
CCOC1=C(C(=CC(=N1)NC(=O)CC2=C(C=CC(=C2)OC)OC)N)C#N

Selective JNK inhibitor

ATP-competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 values are 2, 4 and 52 nM for JNK1, JNK2 and JNK3 respectively). Displays > 1000 fold selectivity over other kinases, including ERK2 and p38. Inhibits c-Jun phosphorylation (EC50 = 920 nM) and prevents collagen-induced platelet aggregation in vitro.
Quantity 10 mg
Formula Weight 356.38
Percent Purity >98%
Chemical Name or Material TCS JNK 6o
Recommended Storage Store at +4°C
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