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TCTN2 Mouse anti-Human, Clone: OTI1C1, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA501477

Catalog No. 50-167-2621


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Description

Description

TCTN2 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN2 is not known, it is 49% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
Specifications

Specifications

TCTN2
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q96GX1
C12orf38, JBTS24, MKS8, TECT2
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
79867
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI1C1
Unconjugated
TCTN2
Liquid
TCTN2
Full length human recombit protein of human TCTN2 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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