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TDG / Thymine-DNA glycosylase Rabbit anti-Mouse, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen TDG / Thymine-DNA glycosylase
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3397 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
61438
10 μL
Each for $135.30
Add to cart
 
50-199-3396 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
61437
100 μL
Each for $534.00
Add to cart
 
Description

Description

The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mis paired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.
Specifications

Specifications

Polyclonal
Primary
TDG / Thymine-DNA glycosylase
Unconjugated
SDS
Product Certifications
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