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TDP-43 Mouse anti-Human, Mouse, Rat, Clone: GT733, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527828

Catalog No. PIMA527828


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Description

Description

Positive Control: A431, HeLa, HepG2, 293T, TARDBP shRNA-transfected 293T, U87-MG, SK-N-SH, IMR32, SK-N-AS Predicted Reactivity: Zebrafish (83%), Xenopus laevis (91%), Chicken (95%), Bovine (96%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Specifications

Specifications

TDP-43
Monoclonal
1 mg/ml
PBS with no preservative
Q13148, Q921F2
TAR DNA binding protein, TDP-43, ALS10
Mouse
IgG1
100 μl
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
230908, 23435, 298648
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
GT733
Unconjugated
TARDBP
Liquid
TARDBP
Recombit protein encompassing a sequence within the center region of human TDP43. The exact sequence is proprietary.
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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