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TdT Mouse anti-Human, Mouse, Rat, Clone: 7UNA8U6, eBioscience™ Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  LIFE TECHNOLOGIES 14973982

Encompass

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Catalog No. 14-973-982


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Description

Description

The MAb 7UNA8U6 reacts with human, mouse, and rat TdT. TdT, or terminal-deoxynucleotidyl transferase, is a 60 kDa polymerase responsible for the template-independent addition of N-nucleotides at gene segment junctions of developing lymphocytes. Expression is found in the nucleus of immature lymphocytes but not in mature lymphocytes or non-lymphoid cells. TdT plays a critical role during TCR and Ig gene rearrangement and functions to increase the diversity of the lymphocyte repertoire through the addition of N-nucleotides onto the ends of newly formed P-nucleotides. After positive selection, expression of TdT becomes decreased or absent. Expression of TdT has been shown to be present in lymphoma or lymphoblastic leukemia cells.

TdT Monoclonal antibody specifically detects TdT in Human, Mouse, Rat samples. It is validated for Immunohistochemistry (Paraffin), Western Blot
Specifications

Specifications

TdT
Immunohistochemistry (Paraffin), Western Blot
7UNA8U6
Unconjugated
DNTT
deoxynucleotidyltransferase, terminal; DNA nucleotidylexotransferase; DNTT; nucleosidetriphosphate:DNA deoxynucleotidylexotransferase; Tdt; terminal addition enzyme; terminal deoxynucleotidyl transferase; terminal deoxynucleotidyltransferase; terminal deoxyribonucleotidyltransferase; terminal transferase
IgG1, kappa
100 μg
4° C
Primary
1791, 21673, 294051
Liquid
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P04053, P09838
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse, Rat
SDS
Documents
Product Certifications
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