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Thermo Scientific Chemicals Telmisartan, 98%, Thermo Scientific Chemicals

Catalog Number aaj6144103
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Quantity:
250 mg
1 g
144701-48-4
C33H30N4O2
BIBR 277; 4′-[(1,4′-Dimethyl-2′-n-propyl[2,6′-bi-1H-benzimidazol]-1′-yl)methyl]biphenyl-2-carboxylic acid
144701-48-4
C33H30N4O2
BIBR 277; 4′-[(1,4′-Dimethyl-2′-n-propyl[2,6′-bi-1H-benzimidazol]-1′-yl)methyl]biphenyl-2-carboxylic acid

An angiotensin II receptor antagonist

Telmisartan also acts as a partial agonist of PPARγ, activating the receptor to 25-30% of that produced by the full agonist rosiglitazone (EC50 = 4.5 ?M). Through these actions, telmisartan potently reduces blood pressure in various animal models of hypertension, diminishing cardiac hypertrophy, cardiovascular and renal risk, and glomerulosclerosis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY
Quantity 1 g
Description White
For Use With (Application) An angiotensin II receptor antagonist
Formula Weight 514.62g/mol
Melting Point 261°C to 263°C
Product Type Signal Transduction Reagent
Form Powder
Assay 99%
Recommended Storage Ambient temperatures

RUO – Research Use Only

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