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  8. tert-Butyl carbazate, 98+%, Thermo Scientific Chemicals

tert-Butyl carbazate, 98+%, Thermo Scientific Chemicals

Catalog Number p-7082105
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Quantity:
25 g
100 g
500 g
870-46-2
C5H12N2O2
132.163
MFCD00007593
DKACXUFSLUYRFU-UHFFFAOYSA-N
tert-butyl carbazate, tert-butyl hydrazinecarboxylate, t-butyl carbazate, hydrazinecarboxylic acid, 1,1-dimethylethyl ester, t-butylcarbazate, tert-butoxycarbonyl hydrazide, boc-hydrazide, boc-hydrazine, tert-butoxycarbonyl hydrazine, carbazic acid tert-butyl ester
70091
tert-butyl N-aminocarbamate
CC(C)(C)OC(=O)NN
870-46-2
C5H12N2O2
132.163
MFCD00007593
DKACXUFSLUYRFU-UHFFFAOYSA-N
tert-butyl carbazate, tert-butyl hydrazinecarboxylate, t-butyl carbazate, hydrazinecarboxylic acid, 1,1-dimethylethyl ester, t-butylcarbazate, tert-butoxycarbonyl hydrazide, boc-hydrazide, boc-hydrazine, tert-butoxycarbonyl hydrazine, carbazic acid tert-butyl ester
70091
tert-butyl N-aminocarbamate
CC(C)(C)OC(=O)NN

Description

tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

Solubility
Soluble in ethanol and methanol.

Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
TRUSTED_SUSTAINABILITY
Melting Point 37°C to 41°C
Boiling Point 63°C to 65°C (0.1 mmHg)
Flash Point 91°C (195°F)
Quantity 25 g
UN Number UN1325
Beilstein 1756967
Sensitivity Moisture sensitive
Solubility Information Soluble in ethanol and methanol.
Formula Weight 132.16
Percent Purity ≥98%
Chemical Name or Material tert-Butyl carbazate
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Safety and Handling

Hazard Category H228-H301+H311-H315-H319-H335
Hazard Statement GHS H Statement
H228
Flammable solid.
Precautionary Statement P210-P240-P241-P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P361-P363-P370+P378q-P501c
DOTInformation Hazard Class: 4.1; Packaging Group: II
EINECSNumber 212-795-3
TSCA Yes
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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