TET1 Mouse anti-Human, Clone: OTI8G6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526527
DescriptionTET1 (tet oncogene 1), also known as LCX or CXXC6, is a 2,136 amino acid protein that localizes to the nucleus and contains one CXXC-type zinc finger. Expressed in adult ovary, thymus and skeletal muscle and also present in fetal lung, heart and brain, TET1 is thought to play a role in the development of fetal organs and may also be involvement in the pathoegenesis and metastasis of acute myeloid leukemia (AML). The gene encoding TET1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman ft.s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|RP11-119F7.1, CXXC6, LCX, bA119F7.1, CXXC finger 6; CXXC zinc finger 6; CXXC-type zinc finger protein 6; leukemia-associated protein with a CXXC domain; methylcytosine dioxygenase TET1; ten-eleven translocation 1 gene protein; ten-eleven translocation-1; tet oncogene 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Human recombit protein fragment corresponding to amino acids 1-305 of TET1 produced in E.coli|
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