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Tocris Bioscience™ TFB-TBOA Available on GSA/VA Contract for Federal Government customers only.

High affinity EAAT1 and EAAT2 blocker

$143.40 - $304.50


Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
25-321 Available on GSA/VA Contract for Federal Government customers only. View Documents Tocris Bioscience™
2532/1
Each for $143.40
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25-321-0 Available on GSA/VA Contract for Federal Government customers only. View Documents Tocris Bioscience™
2532/10
Each for $304.50
Add to cart
 
Description

Description

Potent and selective glial glutamate transporter EAAT1 and EAAT2 inhibitor (IC50 values are 17, 22 and 300 nM for EAAT2, EAAT1 and EAAT3 respectively). Has no effect on EAAT4 and EAAT5, or a wide range of neuronal receptors and transporters. Attenuates glutamate-stimulated intracellular Na+ elevation in astrocytes in vitro (IC50 = 43 nM). Induces severe convulsions in vivo.

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For Research Use Only

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