TFF3 Mouse anti-Human, Clone: OTI4D10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527470
DescriptionTrefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and are clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintece and repair of the intestinal mucosa.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|ITF, P1B, TFI, polypeptide P1.B, trefoil factor 3|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 72-130 of TFF3 produced in E.coli|
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